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Patents And Inventions

Multilayered nanofibrous mucoadhesive films for buccal and sublingual delivery of drug-delivery and
vaccination nanoparticles (Carrier)
J. Mašek, R. Lukáč, M. Raška, P. Turánek-Knötigová, J. Turánek, D. Lubasová, & A. D. Miller

International Application No.: PCT/GB2017/052440, WO2018033744
International Filing Date: 17.8.2017

Mucoadhesive carriers of particles, method of preparation and uses thereof
J. Turánek, J. Mašek, M. Raška, R. Lukáč, P. Knotigová, D. Lubasová, A.D.Miller

International Application No.:   PCT/GB2015/052833, WO2016051159 (A1)
National phase numbers: AU2015326586 (A1), CZ20140665 (A3), EP3200763 (A1), US2017224612 (A1)
International Filing Date: 29.09.2015

The most significant research project FIT achievement was a Czech patent application (PV 2014-665) and subsequently an international patent application which concerns a new system for sublingual non-invasive mucosal vaccination and "technology of printed vaccines".

The present invention relates to a mucoadhesive carrier system, for particles,which comprises nanoscaffold having a nanofibrous layer with a thickness of from 0.1 to 1000 µm, carrying a substance in the form of particles. The mucoadhesive layer,in at least a part of its surface, overlaps the nanoscaffold. A process for its preparation and its use for delivery of the vaccines and therapeutics to mucosal surfaces is also disclosed.

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